The metabolism of Estradiol can be decreased when combined with Imatinib. The serum concentration of Formestane can be increased when it is combined with Estradiol. The therapeutic efficacy of Miglustat can be decreased when used in combination with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Clobazam. Estradiol may decrease the anticoagulant activities of Edetic Acid. The therapeutic efficacy of Ciglitazone can be decreased when used in combination with Estradiol. The metabolism of Estradiol can be decreased when combined with Fluvoxamine. The metabolism of Estradiol can be decreased when combined with Nicardipine. The serum concentration of Estradiol can be increased when it is combined with Ceritinib. The serum concentration of Estradiol can be decreased when it is combined with Batimastat. The serum concentration of Selegiline can be increased when it is combined with Estradiol. Parecoxib may increase the thrombogenic activities of Estradiol. Nabumetone may increase the thrombogenic activities of Estradiol. The serum concentration of Pazopanib can be increased when it is combined with Estradiol. The serum concentration of Equilin can be increased when it is combined with Estradiol. Estradiol may decrease the anticoagulant activities of Certoparin. Estradiol may decrease the anticoagulant activities of Protein S human. The therapeutic efficacy of Insulin Glulisine can be decreased when used in combination with Estradiol. The metabolism of Estradiol can be decreased when combined with Pyrimethamine. The metabolism of Estradiol can be decreased when combined with Nelfinavir. The metabolism of Estradiol can be decreased when combined with Isradipine. Estradiol may decrease the anticoagulant activities of Phenindione. Estradiol may increase the thrombogenic activities of Lenalidomide. The therapeutic efficacy of Exemestane can be decreased when used in combination with Estradiol. Estradiol may decrease the anticoagulant activities of Fondaparinux sodium. The serum concentration of Estradiol can be decreased when it is combined with Fosinopril. The therapeutic efficacy of Nateglinide can be decreased when used in combination with Estradiol. The serum concentration of Androstenedione can be increased when it is combined with Estradiol. The therapeutic efficacy of Estradiol can be decreased when used in combination with Phenytoin. The serum concentration of Betamethasone can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be increased when it is combined with Ivacaftor. The serum concentration of Rimexolone can be increased when it is combined with Estradiol. The metabolism of Estradiol can be decreased when combined with Fluorouracil. The serum concentration of Amcinonide can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Chymostatin. The metabolism of Estradiol can be decreased when combined with Bortezomib. The metabolism of Estradiol can be decreased when combined with Caffeine. The metabolism of Estradiol can be increased when combined with Phenobarbital. The serum concentration of Fluocortolone can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Elvitegravir. The metabolism of Estradiol can be increased when combined with Rifabutin. Estradiol may decrease the anticoagulant activities of Heparin. The metabolism of Estradiol can be decreased when combined with Olaparib. The serum concentration of Estradiol can be decreased when it is combined with Prucalopride. The serum concentration of Desonide can be increased when it is combined with Estradiol. The therapeutic efficacy of Glimepiride can be decreased when used in combination with Estradiol. The metabolism of Estradiol can be decreased when combined with Cimetidine. The therapeutic efficacy of Estradiol can be decreased when used in combination with Thiopental. The serum concentration of Equilenin can be increased when it is combined with Estradiol. Estradiol may decrease the anticoagulant activities of Dicoumarol. The serum concentration of Estradiol can be increased when it is combined with Netupitant. The metabolism of Estradiol can be decreased when combined with Idelalisib. The metabolism of Estradiol can be increased when combined with Pentobarbital. The serum concentration of Estradiol can be decreased when it is combined with Quinapril. The metabolism of Estradiol can be decreased when combined with Clotrimazole. The serum concentration of Estradiol can be decreased when it is combined with Deferasirox. The metabolism of Estradiol can be decreased when combined with Lopinavir. The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Estradiol. Estradiol may decrease the anticoagulant activities of Protein C. Valdecoxib may increase the thrombogenic activities of Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Isoflurophate. The metabolism of Estradiol can be decreased when combined with Sorafenib. The serum concentration of Difluocortolone can be increased when it is combined with Estradiol. The metabolism of Estradiol can be decreased when combined with Omeprazole. The serum concentration of Estradiol can be decreased when it is combined with Zofenopril. The serum concentration of Estradiol can be decreased when it is combined with 3,4-Dichloroisocoumarin. The serum concentration of Flunisolide can be increased when it is combined with Estradiol. The metabolism of Estradiol can be decreased when combined with Theophylline. The serum concentration of Flumethasone can be increased when it is combined with Estradiol. Estradiol may decrease the anticoagulant activities of Dalteparin. Estradiol may decrease the anticoagulant activities of Reviparin. The serum concentration of Estradiol can be decreased when it is combined with Sitagliptin. The serum concentration of Estradiol can be decreased when it is combined with Modafinil. The metabolism of Estradiol can be decreased when combined with Telithromycin. The serum concentration of Estrone can be increased when it is combined with Estradiol. The therapeutic efficacy of Estradiol can be decreased when used in combination with Tipiracil. The serum concentration of Lamotrigine can be decreased when it is combined with Estradiol. The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Estradiol. The metabolism of Estradiol can be decreased when combined with Pantoprazole. The serum concentration of ME-609 can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Imidapril. The therapeutic efficacy of Estradiol can be decreased when used in combination with Adapalene. The serum concentration of Fluticasone propionate can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Darexaban. The serum concentration of Estradiol can be decreased when it is combined with Benazepril. The serum concentration of Estradiol can be decreased when it is combined with Phosphoramidon. The serum concentration of Estradiol can be decreased when it is combined with St. John's Wort. The metabolism of Estradiol can be decreased when combined with Trimethoprim. The serum concentration of Estradiol can be decreased when it is combined with Mycophenolic acid. The serum concentration of Estradiol can be decreased when it is combined with Nitroaspirin. The serum concentration of Estradiol can be decreased when it is combined with Temocapril. Estradiol may decrease the anticoagulant activities of Becaplermin. The serum concentration of Difluprednate can be increased when it is combined with Estradiol. The serum concentration of Fluocinolone Acetonide can be increased when it is combined with Estradiol. The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Bexarotene. The metabolism of Estradiol can be decreased when combined with Losartan. The therapeutic efficacy of Acarbose can be decreased when used in combination with Estradiol. Estradiol may increase the dermatologic adverse activities of Tipranavir. The serum concentration of Estradiol can be decreased when it is combined with Boceprevir. The metabolism of Estradiol can be increased when combined with Rifampicin. The metabolism of Estradiol can be decreased when combined with Erythromycin. The serum concentration of Estradiol can be decreased when it is combined with Ximelagatran. The serum concentration of Clobetasone can be increased when it is combined with Estradiol. The serum concentration of Oleoyl-estrone can be increased when it is combined with Estradiol. Estradiol may decrease the anticoagulant activities of Acenocoumarol. The serum concentration of Estradiol can be decreased when it is combined with Rifaximin. The serum concentration of Estradiol can be decreased when it is combined with Oxcarbazepine. The therapeutic efficacy of Glyburide can be decreased when used in combination with Estradiol. The serum concentration of Deflazacort can be increased when it is combined with Estradiol. Estradiol may increase the thrombogenic activities of Thalidomide. Estradiol may decrease the anticoagulant activities of Ferulic acid. The serum concentration of Estradiol can be decreased when it is combined with Cyproterone acetate. The serum concentration of Estradiol can be decreased when it is combined with N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline. The metabolism of Estradiol can be decreased when combined with Quinine. The metabolism of Estradiol can be decreased when combined with Crisaborole. The metabolism of Estradiol can be decreased when combined with Fluoxetine. The serum concentration of Estradiol can be decreased when it is combined with Ixazomib. Estradiol may increase the thrombogenic activities of Anthrax immune globulin human. The serum concentration of Estradiol can be increased when it is combined with Dasatinib. The serum concentration of Estradiol can be decreased when it is combined with Faldaprevir. The serum concentration of Estradiol can be decreased when it is combined with Cholesterol. The serum concentration of Estradiol can be decreased when it is combined with Tocilizumab. The serum concentration of Estradiol can be increased when it is combined with Fusidic Acid. The serum concentration of Estradiol can be decreased when it is combined with Cobicistat. Estradiol may decrease the anticoagulant activities of Ardeparin. The metabolism of Estradiol can be decreased when combined with Ketoconazole. The serum concentration of HE3286 can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Dabrafenib. The serum concentration of Estradiol can be decreased when it is combined with Omapatrilat.