The serum concentration of Valproic Acid can be increased when it is combined with Guanfacine. The metabolism of Lumiracoxib can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Tetrabenazine. The serum concentration of Valproic Acid can be decreased when it is combined with Lisinopril. Valproic Acid may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. The risk or severity of adverse effects can be increased when Quetiapine is combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Isoniazid. The metabolism of Etoricoxib can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be increased when it is combined with Luliconazole. The risk or severity of adverse effects can be increased when Bromazepam is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Zaleplon is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Tramadol is combined with Valproic Acid. The metabolism of Dicoumarol can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Procaine. The metabolism of Theophylline can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be increased when it is combined with Quazepam. The serum concentration of Valproic Acid can be decreased when it is combined with Enalapril. The serum concentration of Olanzapine can be decreased when it is combined with Valproic Acid. The metabolism of Ketoprofen can be decreased when combined with Valproic Acid. Valproic Acid may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. The metabolism of Rosuvastatin can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Lurasidone is combined with Valproic Acid. The metabolism of Metronidazole can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Clidinium. The metabolism of Niclosamide can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Butalbital. The serum concentration of Barbexaclone can be increased when it is combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Fosinopril. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Ketobemidone. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Chlorprothixene. The metabolism of Seratrodast can be decreased when combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Citalopram. The serum concentration of Valproic Acid can be decreased when it is combined with Letaxaban. The metabolism of Zileuton can be decreased when combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Etravirine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Fexofenadine. The therapeutic efficacy of Valproic Acid can be decreased when used in combination with Mefloquine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Fospropofol. The risk or severity of adverse effects can be increased when Remifentanil is combined with Valproic Acid. The serum concentration of Mevastatin can be increased when it is combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Rucaparib. The metabolism of Sulfamoxole can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Ixazomib. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Normethadone. The serum concentration of Nortriptyline can be increased when it is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Ecopipam. The risk or severity of adverse effects can be increased when Reserpine is combined with Valproic Acid. The serum concentration of Amodiaquine can be increased when it is combined with Valproic Acid. The metabolism of Rofecoxib can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Ketazolam. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Cyclizine. The serum concentration of Valproic Acid can be decreased when it is combined with Omapatrilat. The metabolism of Dolasetron can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Desloratadine. The metabolism of Terfenadine can be decreased when combined with Valproic Acid. The metabolism of Cabozantinib can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Perindopril. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Phenoxyethanol. The serum concentration of Valproic Acid can be increased when it is combined with Felbamate. The metabolism of Imatinib can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Triazolam is combined with Valproic Acid. The serum concentration of Clomipramine can be increased when it is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Clonidine. The risk or severity of adverse effects can be increased when Buspirone is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Flibanserin. The serum concentration of Valproic Acid can be decreased when it is combined with Saxagliptin. The serum concentration of Valproic Acid can be decreased when it is combined with Captopril. The metabolism of Valproic Acid can be decreased when combined with Quinine. The serum concentration of Valproic Acid can be decreased when it is combined with Benazepril. The serum concentration of Valproic Acid can be decreased when it is combined with Meropenem. The metabolism of Valproic Acid can be decreased when combined with Sorafenib. The metabolism of Proguanil can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Methadyl Acetate. The risk or severity of adverse effects can be increased when Butabarbital is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Dezocine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Halothane. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Metaxalone. The serum concentration of Valproic Acid can be decreased when it is combined with Prinomastat. The metabolism of Dapsone can be decreased when combined with Valproic Acid. The metabolism of Tenoxicam can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Trichloroethylene. The risk or severity of adverse effects can be increased when Pethidine is combined with Valproic Acid. The metabolism of Dorzolamide can be decreased when combined with Valproic Acid. The serum concentration of Secobarbital can be increased when it is combined with Valproic Acid. The metabolism of Phenylbutazone can be decreased when combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Delavirdine. The metabolism of Gavestinel can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Dexbrompheniramine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Pizotifen. The risk or severity of adverse effects can be increased when Perphenazine is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with DPDPE. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Zotepine. The metabolism of Valproic Acid can be decreased when combined with Doxorubicin. The serum concentration of Valproic Acid can be decreased when it is combined with Lumacaftor. The metabolism of Phenprocoumon can be decreased when combined with Valproic Acid. The metabolism of Selegiline can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Imidapril. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Zonisamide. The metabolism of Valproic Acid can be decreased when combined with Esomeprazole. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Articaine. The risk or severity of adverse effects can be increased when Asenapine is combined with Valproic Acid. The metabolism of Formoterol can be decreased when combined with Valproic Acid. The metabolism of Montelukast can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be increased when it is combined with Carbaspirin calcium. The serum concentration of Valproic Acid can be decreased when it is combined with Fosamprenavir. The serum concentration of Bosentan can be increased when it is combined with Valproic Acid. Nabilone may increase the central nervous system depressant (CNS depressant) activities of Valproic Acid. The metabolism of Caffeine can be decreased when combined with Valproic Acid. The metabolism of Mestranol can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Alogliptin. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Desvenlafaxine. The risk or severity of adverse effects can be increased when Loxapine is combined with Valproic Acid. The metabolism of Pitavastatin can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Ropivacaine is combined with Valproic Acid. The metabolism of Naproxen can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Dexmedetomidine. The serum concentration of Valproic Acid can be decreased when it is combined with Doripenem. The risk or severity of adverse effects can be increased when Alprazolam is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Piritramide. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Deramciclane. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Ethyl loflazepate. The metabolism of Idarubicin can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Lithium. The metabolism of Gliclazide can be decreased when combined with Valproic Acid. The metabolism of Bexarotene can be decreased when combined with Valproic Acid. The metabolism of Glyburide can be decreased when combined with Valproic Acid. The metabolism of Lansoprazole can be decreased when combined with Valproic Acid. Valproic Acid may increase the thrombocytopenic activities of Vorinostat.