The metabolism of Lesinurad can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be increased when it is combined with Diflunisal. The metabolism of Torasemide can be decreased when combined with Valproic Acid. The metabolism of Nateglinide can be decreased when combined with Valproic Acid. Droperidol may increase the central nervous system depressant (CNS depressant) activities of Valproic Acid. The serum concentration of Opipramol can be increased when it is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Remoxipride. The metabolism of Valproic Acid can be decreased when combined with Valsartan. The metabolism of Mefenamic acid can be decreased when combined with Valproic Acid. The metabolism of Dapagliflozin can be decreased when combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Topiroxostat. The serum concentration of Valproic Acid can be decreased when it is combined with Darunavir. The metabolism of Valproic Acid can be decreased when combined with Sulfadiazine. The serum concentration of Valproic Acid can be decreased when it is combined with Omapatrilat. The metabolism of Rosiglitazone can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be increased when it is combined with Salicylic acid. The metabolism of Rupatadine can be decreased when combined with Valproic Acid. The metabolism of Gliclazide can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be increased when it is combined with Carbaspirin calcium. The metabolism of Licofelone can be decreased when combined with Valproic Acid. The metabolism of Warfarin can be decreased when combined with Valproic Acid. Valproic Acid may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. The serum concentration of Nortriptyline can be increased when it is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Desflurane is combined with Valproic Acid. The serum concentration of Trimipramine can be increased when it is combined with Valproic Acid. The metabolism of Paramethadione can be decreased when combined with Valproic Acid. The metabolism of Estrone can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Ondansetron. The serum concentration of Valproic Acid can be increased when it is combined with Olsalazine. The metabolism of Troglitazone can be decreased when combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Losartan. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Butalbital. The metabolism of Valproic Acid can be decreased when combined with Pyrimethamine. The metabolism of Quinidine can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Enflurane is combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline. The metabolism of Valproic Acid can be decreased when combined with Ticlopidine. The metabolism of Netupitant can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Apixaban. The metabolism of Bupropion can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Bivalirudin. The serum concentration of Valproic Acid can be decreased when it is combined with Cholesterol. The risk or severity of adverse effects can be increased when Flurazepam is combined with Valproic Acid. The metabolism of Donepezil can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Indinavir. The serum concentration of Valproic Acid can be decreased when it is combined with Spirapril. The serum concentration of Bosutinib can be increased when it is combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with 4-(2-Aminoethyl)Benzenesulfonyl Fluoride. The metabolism of Valproic Acid can be decreased when combined with Quinine. The metabolism of Meloxicam can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Methocarbamol. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Fencamfamine. The metabolism of Clopidogrel can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Oxprenolol. The serum concentration of Ubidecarenone can be increased when it is combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Stiripentol. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Pomalidomide. The metabolism of Valproic Acid can be decreased when combined with Midostaurin. The serum concentration of Valproic Acid can be increased when it is combined with Chlorpromazine. The metabolism of Candesartan cilexetil can be decreased when combined with Valproic Acid. The metabolism of Etodolac can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Ulinastatin. The risk or severity of adverse effects can be increased when Estazolam is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Aripiprazole is combined with Valproic Acid. The metabolism of Sulfamoxole can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Methsuximide. Valproic Acid may increase the sedative activities of Pramipexole. The risk or severity of adverse effects can be increased when Oxymorphone is combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Boceprevir. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Scopolamine. Valproic Acid may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. The serum concentration of Valproic Acid can be decreased when it is combined with Ethosuximide. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Pipamperone. The risk or severity of adverse effects can be increased when Valproic Acid is combined with DPDPE. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Dextropropoxyphene. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Chlorphenamine. The metabolism of Terfenadine can be decreased when combined with Valproic Acid. The metabolism of Trimethadione can be decreased when combined with Valproic Acid. The metabolism of Valproic Acid can be decreased when combined with Sertraline. The metabolism of Acenocoumarol can be decreased when combined with Valproic Acid. The serum concentration of Paliperidone can be increased when it is combined with Valproic Acid. Valproic Acid may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. The risk or severity of adverse effects can be increased when Methysergide is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Dexbrompheniramine. The serum concentration of Valproic Acid can be decreased when it is combined with Orlistat. The metabolism of Rosuvastatin can be decreased when combined with Valproic Acid. The serum concentration of Valproic Acid can be decreased when it is combined with Saxagliptin. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Dyclonine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Chlormezanone. The risk or severity of adverse effects can be increased when Lisuride is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Dexmedetomidine. The risk or severity of adverse effects can be increased when Propofol is combined with Valproic Acid. The serum concentration of Carvedilol can be increased when it is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Levorphanol is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Etoperidone. The serum concentration of Esmirtazapine can be increased when it is combined with Valproic Acid. The metabolism of Chlorpropamide can be decreased when combined with Valproic Acid. The serum concentration of Thiopental can be increased when it is combined with Valproic Acid. The metabolism of Parecoxib can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Fospropofol. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Entacapone. The metabolism of Valproic Acid can be decreased when combined with Cyclosporine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Carisoprodol. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Norflurane. The metabolism of Lumiracoxib can be decreased when combined with Valproic Acid. The metabolism of Glyburide can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Pizotifen. The serum concentration of Valproic Acid can be decreased when it is combined with Rifampicin. The metabolism of Valproic Acid can be decreased when combined with Crizotinib. The serum concentration of Valproic Acid can be decreased when it is combined with Asunaprevir. The metabolism of Zaltoprofen can be decreased when combined with Valproic Acid. The therapeutic efficacy of Phenylacetic acid can be decreased when used in combination with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Ketazolam. The risk or severity of adverse effects can be increased when Pentazocine is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Proparacaine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Levodopa. The serum concentration of Valproic Acid can be decreased when it is combined with Delanzomib. The metabolism of Valproic Acid can be decreased when combined with Fluvoxamine. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Chlorzoxazone. The metabolism of Epoprostenol can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Etorphine. The metabolism of Dorzolamide can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Lysergic Acid Diethylamide is combined with Valproic Acid. The risk or severity of adverse effects can be increased when Valproic Acid is combined with Chloral hydrate. The metabolism of Valproic Acid can be decreased when combined with Clotrimazole. The metabolism of Celecoxib can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Bupivacaine is combined with Valproic Acid. Valproic Acid may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. The serum concentration of Valproic Acid can be decreased when it is combined with 1,10-Phenanthroline.