The therapeutic efficacy of Dextran 75 can be decreased when used in combination with Levonorgestrel. The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Levonorgestrel. The metabolism of Levonorgestrel can be increased when combined with Rifabutin. The therapeutic efficacy of Bempedoic acid can be decreased when used in combination with Estradiol. The therapeutic efficacy of Estradiol can be decreased when used in combination with Acitretin. The metabolism of Estradiol can be decreased when combined with Imatinib. The serum concentration of Estradiol can be decreased when it is combined with Colestipol. The metabolism of Estradiol can be increased when combined with Primidone. The serum concentration of Estradiol can be increased when it is combined with Luliconazole. The serum concentration of Estradiol can be decreased when it is combined with Alogliptin. The serum concentration of Estradiol can be decreased when it is combined with Armodafinil. The metabolism of Estradiol can be decreased when combined with Manidipine. The metabolism of Estradiol can be decreased when combined with Moclobemide. The serum concentration of Estradiol can be decreased when it is combined with N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline. The therapeutic efficacy of Apixaban can be decreased when used in combination with Levonorgestrel. The therapeutic efficacy of Voglibose can be decreased when used in combination with Levonorgestrel. The serum concentration of Estradiol can be decreased when it is combined with Dabigatran etexilate. The serum concentration of Pregnenolone can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Racecadotril. The serum concentration of Fluocinolone Acetonide can be increased when it is combined with Estradiol. The therapeutic efficacy of Canagliflozin can be decreased when used in combination with Levonorgestrel. Estradiol may decrease the anticoagulant activities of Acenocoumarol. The serum concentration of Estradiol can be decreased when it is combined with Delanzomib. The serum concentration of Saxagliptin can be decreased when it is combined with Estradiol. The metabolism of Estradiol can be decreased when combined with Ticlopidine. The serum concentration of Estradiol can be decreased when it is combined with Benzamidine. The metabolism of Estradiol can be decreased when combined with Sertraline. The serum concentration of Ropinirole can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Gabexate. The metabolism of Levonorgestrel can be decreased when combined with Doxycycline. Estradiol may decrease the anticoagulant activities of Nadroparin. The serum concentration of Cortexolone 17α-propionate can be increased when it is combined with Estradiol. The therapeutic efficacy of Argatroban can be decreased when used in combination with Levonorgestrel. The serum concentration of Estradiol can be decreased when it is combined with Batimastat. The therapeutic efficacy of Glimepiride can be decreased when used in combination with Levonorgestrel. The serum concentration of Estradiol can be decreased when it is combined with Ramipril. The metabolism of Estradiol can be decreased when combined with Leflunomide. Estradiol may decrease the anticoagulant activities of Fondaparinux. The serum concentration of Desoxycorticosterone Pivalate can be increased when it is combined with Estradiol. The serum concentration of Dexamethasone can be increased when it is combined with Estradiol. The metabolism of Estradiol can be decreased when combined with Dihydroergotamine. The metabolism of Estradiol can be decreased when combined with Verapamil. The therapeutic efficacy of Dextran 70 can be decreased when used in combination with Levonorgestrel. The serum concentration of 5-androstenedione can be increased when it is combined with Estradiol. Estradiol may decrease the anticoagulant activities of Dextran 70. The serum concentration of Estradiol can be decreased when it is combined with Enalapril. The metabolism of Estradiol can be increased when combined with Rifampicin. Estradiol may decrease the anticoagulant activities of Phenprocoumon. The serum concentration of Pazopanib can be increased when it is combined with Estradiol. The therapeutic efficacy of Glibornuride can be decreased when used in combination with Levonorgestrel. The serum concentration of Levonorgestrel can be decreased when it is combined with Aprepitant. The therapeutic efficacy of Estradiol can be decreased when used in combination with Amobarbital. Estradiol may decrease the anticoagulant activities of Reviparin. The serum concentration of Fludrocortisone can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be increased when it is combined with Abiraterone. The serum concentration of Estradiol can be decreased when it is combined with Tocilizumab. The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Adapalene. The serum concentration of Estradiol can be decreased when it is combined with 1,10-Phenanthroline. The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Levonorgestrel. The serum concentration of Conivaptan can be increased when it is combined with Estradiol. The therapeutic efficacy of Dextran 40 can be decreased when used in combination with Levonorgestrel. The metabolism of Levonorgestrel can be decreased when combined with Lovastatin. The metabolism of Estradiol can be decreased when combined with Atomoxetine. The serum concentration of Corticosterone can be increased when it is combined with Estradiol. The metabolism of Estradiol can be decreased when combined with Lobeglitazone. The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Estradiol. The metabolism of Estradiol can be decreased when combined with Quinine. The serum concentration of Estradiol can be decreased when it is combined with Sitagliptin. The therapeutic efficacy of Estradiol can be decreased when used in combination with Adapalene. The metabolism of Estradiol can be decreased when combined with Bortezomib. The metabolism of Levonorgestrel can be decreased when combined with Nefazodone. The serum concentration of Levonorgestrel can be increased when it is combined with Osimertinib. The serum concentration of Levonorgestrel can be decreased when it is combined with Lumacaftor. The metabolism of Estradiol can be decreased when combined with Clarithromycin. The serum concentration of Levonorgestrel can be increased when it is combined with Stiripentol. The metabolism of Estradiol can be decreased when combined with Dosulepin. The therapeutic efficacy of Insulin Glargine can be decreased when used in combination with Estradiol. The therapeutic efficacy of Darexaban can be decreased when used in combination with Levonorgestrel. The serum concentration of Equilenin can be increased when it is combined with Estradiol. The metabolism of Levonorgestrel can be decreased when combined with Fluvoxamine. Estradiol may decrease the anticoagulant activities of Enoxaparin. The serum concentration of Estradiol can be decreased when it is combined with Captopril. The therapeutic efficacy of Phenformin can be decreased when used in combination with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Phosphoramidon. The serum concentration of Tizanidine can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Lumacaftor. Estradiol may decrease the anticoagulant activities of Ardeparin. Estradiol may decrease the anticoagulant activities of Desirudin. Levonorgestrel may decrease the anticoagulant activities of Warfarin. Estradiol may increase the thrombogenic activities of Anthrax immune globulin human. The serum concentration of Estradiol can be decreased when it is combined with Enalkiren. Levonorgestrel may increase the thrombogenic activities of Human C1-esterase inhibitor. The metabolism of Estradiol can be decreased when combined with Isoniazid. The therapeutic efficacy of Allicin can be decreased when used in combination with Estradiol. The metabolism of Estradiol can be decreased when combined with Fluorouracil. The serum concentration of Estradiol can be decreased when it is combined with Letaxaban. The metabolism of Estradiol can be decreased when combined with Crizotinib. The serum concentration of Estradiol can be decreased when it is combined with Modafinil. The metabolism of Levonorgestrel can be decreased when combined with Crizotinib. The serum concentration of Betamethasone can be increased when it is combined with Estradiol. The therapeutic efficacy of Insulin Glulisine can be decreased when used in combination with Levonorgestrel. The metabolism of Estradiol can be decreased when combined with Lopinavir. The serum concentration of Estradiol can be decreased when it is combined with Benazepril. Estradiol may increase the thrombogenic activities of Thalidomide. The serum concentration of Estradiol can be decreased when it is combined with Rifaximin. The therapeutic efficacy of Troxerutin can be decreased when used in combination with Levonorgestrel. Parecoxib may increase the thrombogenic activities of Estradiol. The therapeutic efficacy of Sulodexide can be decreased when used in combination with Levonorgestrel. The metabolism of Estradiol can be increased when combined with Secobarbital. The therapeutic efficacy of Miglustat can be decreased when used in combination with Levonorgestrel. The metabolism of Levonorgestrel can be decreased when combined with Dihydroergotamine. The serum concentration of Flibanserin can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Spirapril. The serum concentration of Fluorometholone can be increased when it is combined with Estradiol. The serum concentration of Levonorgestrel can be decreased when it is combined with Nevirapine. The therapeutic efficacy of Chenodeoxycholic acid can be decreased when used in combination with Estradiol. The therapeutic efficacy of Ciglitazone can be decreased when used in combination with Levonorgestrel. The serum concentration of Estradiol can be decreased when it is combined with Amprenavir. The serum concentration of Levonorgestrel can be increased when it is combined with Palbociclib. The risk or severity of adverse effects can be increased when Estradiol is combined with Ospemifene. Estradiol may increase the thrombogenic activities of Conestat alfa. The serum concentration of Estrone sulfate can be increased when it is combined with Estradiol. The serum concentration of Fluocinonide can be increased when it is combined with Estradiol. The serum concentration of Estradiol can be decreased when it is combined with Fosaprepitant. The metabolism of Estradiol can be decreased when combined with Sildenafil. The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Estradiol. The serum concentration of Levonorgestrel can be decreased when it is combined with Oxcarbazepine. Levonorgestrel may decrease the anticoagulant activities of Dicoumarol. Tranexamic Acid may increase the thrombogenic activities of Levonorgestrel. The therapeutic efficacy of Ardeparin can be decreased when used in combination with Levonorgestrel.