The risk or severity of adverse effects can be increased when Alprazolam is combined with Prochlorperazine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Molindone. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Adipiplon. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ethylmorphine. The serum concentration of Alprazolam can be increased when it is combined with Edoxaban. The risk or severity of adverse effects can be increased when Alprazolam is combined with Isoflurane. The risk or severity of adverse effects can be increased when Alprazolam is combined with Etomidate. The risk or severity of adverse effects can be increased when Alprazolam is combined with Clobazam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ketobemidone. Alprazolam may increase the sedative activities of Rotigotine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Flibanserin. The risk or severity of adverse effects can be increased when Alprazolam is combined with Dihydromorphine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Diazepam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Pomalidomide. The serum concentration of Alprazolam can be decreased when it is combined with Bosentan. The risk or severity of adverse effects can be increased when Alprazolam is combined with Triazolam. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Methadone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Fexofenadine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Zaleplon. The serum concentration of Alprazolam can be increased when it is combined with Luliconazole. The risk or severity of adverse effects can be increased when Alprazolam is combined with Pimozide. The risk or severity of adverse effects can be increased when Alprazolam is combined with Meclizine. The metabolism of Alprazolam can be decreased when combined with Pyrimethamine. The metabolism of Alprazolam can be decreased when combined with Fluvastatin. The serum concentration of Alprazolam can be increased when it is combined with N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline. The risk or severity of adverse effects can be increased when Alprazolam is combined with Remoxipride. The metabolism of Alprazolam can be increased when combined with Rifabutin. The risk or severity of adverse effects can be increased when Alprazolam is combined with Thioridazine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Melatonin. The risk or severity of adverse effects can be increased when Alprazolam is combined with Topiramate. The serum concentration of Alprazolam can be increased when it is combined with Bivalirudin. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. The metabolism of Alprazolam can be decreased when combined with Manidipine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Midazolam. The risk or severity of adverse effects can be increased when Codeine is combined with Alprazolam. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Duloxetine. The serum concentration of Alprazolam can be increased when it is combined with Darexaban. The therapeutic efficacy of Alprazolam can be decreased when used in combination with Theophylline. The metabolism of Alprazolam can be decreased when combined with Fluconazole. The risk or severity of adverse effects can be increased when Alprazolam is combined with Pethidine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Dezocine. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. The risk or severity of adverse effects can be increased when Alprazolam is combined with Sulpiride. The serum concentration of Mevastatin can be increased when it is combined with Alprazolam. The serum concentration of Alprazolam can be increased when it is combined with Alpha-1-proteinase inhibitor. The risk or severity of adverse effects can be increased when Alprazolam is combined with Haloperidol. The risk or severity of adverse effects can be increased when Alprazolam is combined with Drotebanol. The risk or severity of adverse effects can be increased when Alprazolam is combined with Perphenazine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Oxybuprocaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Tetrahydropalmatine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Etidocaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Nitrous oxide. The risk or severity of adverse effects can be increased when Alprazolam is combined with Dantrolene. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Azelastine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Butalbital. The serum concentration of Alprazolam can be increased when it is combined with Saxagliptin. The serum concentration of Alprazolam can be increased when it is combined with Fosaprepitant. The serum concentration of Alprazolam can be increased when it is combined with Elafin. The metabolism of Alprazolam can be decreased when combined with Nicardipine. The serum concentration of Alprazolam can be increased when it is combined with Simeprevir. The risk or severity of adverse effects can be increased when Alprazolam is combined with Chlormezanone. The serum concentration of Alprazolam can be increased when it is combined with Osimertinib. The risk or severity of adverse effects can be increased when Metergoline is combined with Alprazolam. The serum concentration of Alprazolam can be increased when it is combined with Ubenimex. The metabolism of Alprazolam can be decreased when combined with Omeprazole. The risk or severity of adverse effects can be increased when Eszopiclone is combined with Alprazolam. The serum concentration of Alprazolam can be increased when it is combined with Linagliptin. The serum concentration of Alprazolam can be increased when it is combined with Netupitant. The risk or severity of adverse effects can be increased when Alprazolam is combined with Desipramine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Lormetazepam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Acepromazine. Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Alprazolam. The serum concentration of Alprazolam can be increased when it is combined with Nafamostat. The risk or severity of adverse effects can be increased when Alprazolam is combined with Clozapine. The serum concentration of Alprazolam can be increased when it is combined with Spirapril. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ondansetron. The risk or severity of adverse effects can be increased when Alprazolam is combined with Flurazepam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Cocaine. The metabolism of Alprazolam can be decreased when combined with Olaparib. The risk or severity of adverse effects can be increased when Alprazolam is combined with Sepranolone. The serum concentration of Alprazolam can be increased when it is combined with Candoxatril. The metabolism of Alprazolam can be decreased when combined with Etravirine. The serum concentration of Alprazolam can be increased when it is combined with Ritonavir. The serum concentration of Alprazolam can be increased when it is combined with Argatroban. The serum concentration of Alprazolam can be increased when it is combined with Thiorphan. The serum concentration of Alprazolam can be increased when it is combined with S-3304. The serum concentration of Alprazolam can be increased when it is combined with Clarithromycin. The risk or severity of adverse effects can be increased when Alprazolam is combined with Fospropofol. The serum concentration of Alprazolam can be increased when it is combined with Ecabet. The metabolism of Alprazolam can be decreased when combined with Ticagrelor. The risk or severity of adverse effects can be increased when Nicergoline is combined with Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Etizolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Zopiclone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Nalbuphine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Risperidone. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. The therapeutic efficacy of Alprazolam can be decreased when used in combination with Hyaluronidase. The risk or severity of adverse effects can be increased when Alprazolam is combined with Butethal. The serum concentration of Alprazolam can be increased when it is combined with Ramipril. The serum concentration of Bosutinib can be increased when it is combined with Alprazolam. The serum concentration of Pitavastatin can be increased when it is combined with Alprazolam. The serum concentration of Alprazolam can be increased when it is combined with Isoflurophate. The metabolism of Alprazolam can be decreased when combined with Dronedarone. The serum concentration of Alprazolam can be increased when it is combined with Telithromycin. The risk or severity of adverse effects can be increased when Alprazolam is combined with Pipamperone. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Normethadone. The serum concentration of Alprazolam can be increased when it is combined with Enalaprilat. The serum concentration of Simvastatin can be increased when it is combined with Alprazolam. The risk or severity of adverse effects can be increased when Lorazepam is combined with Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Olanzapine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Mepivacaine. The metabolism of Alprazolam can be decreased when combined with Irbesartan. The serum concentration of Alprazolam can be increased when it is combined with Perindopril. The risk or severity of adverse effects can be increased when Alprazolam is combined with Butamben. The therapeutic efficacy of Alprazolam can be decreased when used in combination with Yohimbine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Phenoxyethanol. The risk or severity of adverse effects can be increased when Alprazolam is combined with Trichloroethylene. The risk or severity of adverse effects can be increased when Alprazolam is combined with Alphaprodine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ethotoin. The risk or severity of adverse effects can be increased when Tramadol is combined with Alprazolam. The serum concentration of Alprazolam can be increased when it is combined with Teduglutide. The serum concentration of Alprazolam can be increased when it is combined with Temocapril. The risk or severity of adverse effects can be increased when Alprazolam is combined with Melperone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Zuclopenthixol. The metabolism of Alprazolam can be decreased when combined with Gemfibrozil. The serum concentration of Fosphenytoin can be increased when it is combined with Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Levomethadyl Acetate.