The risk or severity of adverse effects can be increased when Isoniazid is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Fluoxetine. The metabolism of Acetaminophen can be decreased when combined with Clotrimazole. The metabolism of Acetaminophen can be decreased when combined with Cholecalciferol. The metabolism of Acetaminophen can be decreased when combined with Zucapsaicin. The metabolism of Acetaminophen can be decreased when combined with Cimetidine. Cholestyramine can cause a decrease in the absorption of Acetaminophen resulting in a reduced serum concentration and potentially a decrease in efficacy. The metabolism of Acetaminophen can be decreased when combined with Manidipine. The metabolism of Acetaminophen can be decreased when combined with Zafirlukast. The metabolism of Acetaminophen can be decreased when combined with Bupropion. The metabolism of Acetaminophen can be decreased when combined with Tolbutamide. The metabolism of Acetaminophen can be decreased when combined with Clarithromycin. The metabolism of Acetaminophen can be decreased when combined with Efavirenz. The serum concentration of Rifaximin can be increased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Indinavir. The serum concentration of Vincristine can be increased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be increased when combined with Phenobarbital. The metabolism of Acetaminophen can be decreased when combined with Cinacalcet. The metabolism of Acetaminophen can be increased when combined with Rifapentine. The risk or severity of adverse effects can be increased when Methysergide is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Rolapitant. The serum concentration of Acetaminophen can be increased when it is combined with Probenecid. The metabolism of Acetaminophen can be decreased when combined with Tranylcypromine. The metabolism of Acetaminophen can be decreased when combined with Capecitabine. The serum concentration of Rosuvastatin can be increased when it is combined with Acetaminophen. The risk or severity of adverse effects can be increased when Bromocriptine is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Topiroxostat. The metabolism of Acetaminophen can be increased when combined with Thiamylal. The metabolism of Acetaminophen can be decreased when combined with Dihydroergotamine. The metabolism of Acetaminophen can be decreased when combined with Duloxetine. The metabolism of Acetaminophen can be increased when combined with Methylphenobarbital. The serum concentration of Acetaminophen can be increased when it is combined with Mifepristone. The metabolism of Acetaminophen can be decreased when combined with Leflunomide. The metabolism of Acetaminophen can be decreased when combined with Saquinavir. The serum concentration of Nintedanib can be increased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Losartan. The metabolism of Acetaminophen can be decreased when combined with Valsartan. Acetaminophen may increase the hepatotoxic activities of Sorafenib. The serum concentration of Acetaminophen can be decreased when it is combined with Phenytoin. The serum concentration of Prucalopride can be increased when it is combined with Acetaminophen. The risk or severity of adverse effects can be increased when Acetaminophen is combined with Sodium Nitrite. The serum concentration of Acetaminophen can be decreased when it is combined with Fosphenytoin. The metabolism of Acetaminophen can be decreased when combined with Imipramine. The serum concentration of Naloxegol can be increased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Fluvoxamine. The serum concentration of Acetaminophen can be increased when it is combined with Osimertinib. The risk or severity of adverse effects can be increased when Ergonovine is combined with Acetaminophen. The risk or severity of adverse effects can be increased when Acetaminophen is combined with Prilocaine. The metabolism of Acetaminophen can be decreased when combined with Nefazodone. The metabolism of Acetaminophen can be decreased when combined with Fluorouracil. The metabolism of Acetaminophen can be decreased when combined with Sildenafil. The metabolism of Acetaminophen can be decreased when combined with Mirabegron. The risk or severity of adverse effects can be increased when Lysergic Acid Diethylamide is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Sertraline. The metabolism of Acetaminophen can be decreased when combined with Isradipine. The metabolism of Acetaminophen can be decreased when combined with Nicardipine. The metabolism of Acetaminophen can be decreased when combined with Ropinirole. The serum concentration of Acetaminophen can be decreased when it is combined with Teriflunomide. The metabolism of Acetaminophen can be decreased when combined with Lopinavir. The serum concentration of Acetaminophen can be increased when it is combined with Simeprevir. The metabolism of Acetaminophen can be decreased when combined with Nicotine. The metabolism of Acetaminophen can be decreased when combined with Verapamil. The metabolism of Acetaminophen can be decreased when combined with Haloperidol. The metabolism of Acetaminophen can be decreased when combined with Chloroquine. The metabolism of Acetaminophen can be decreased when combined with Isavuconazonium. The serum concentration of Acetaminophen can be decreased when it is combined with St. John's Wort. The metabolism of Acetaminophen can be decreased when combined with Voriconazole. The serum concentration of Afatinib can be increased when it is combined with Acetaminophen. The serum concentration of Acetaminophen can be increased when it is combined with Metyrapone. Acetaminophen may increase the anticoagulant activities of Warfarin. The metabolism of Acetaminophen can be increased when combined with Thiopental. The metabolism of Acetaminophen can be decreased when combined with Caffeine. The metabolism of Acetaminophen can be decreased when combined with Telaprevir. The metabolism of Acetaminophen can be decreased when combined with Lovastatin. Acetaminophen may increase the anticoagulant activities of Phenprocoumon. The serum concentration of Silodosin can be increased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Celecoxib. The serum concentration of Conivaptan can be increased when it is combined with Acetaminophen. The serum concentration of Saxagliptin can be decreased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Pyrimethamine. The metabolism of Acetaminophen can be decreased when combined with Lapatinib. The serum concentration of Everolimus can be increased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be increased when combined with Carbamazepine. The serum concentration of Phenylephrine can be increased when it is combined with Acetaminophen. The serum concentration of Acetaminophen can be decreased when it is combined with Siltuximab. The metabolism of Acetaminophen can be decreased when combined with Chlorpromazine. The metabolism of Acetaminophen can be decreased when combined with Nelfinavir. The metabolism of Acetaminophen can be decreased when combined with Terbinafine. The serum concentration of Ledipasvir can be increased when it is combined with Acetaminophen. The metabolism of Acetaminophen can be decreased when combined with Artemether. The serum concentration of Acetaminophen can be decreased when it is combined with Tocilizumab. The metabolism of Acetaminophen can be increased when combined with Nevirapine. The metabolism of Acetaminophen can be decreased when combined with Lumefantrine. The metabolism of Acetaminophen can be decreased when combined with Ritonavir. The serum concentration of Acetaminophen can be decreased when it is combined with Deferasirox. The serum concentration of Topotecan can be increased when it is combined with Acetaminophen. Acetaminophen may increase the hepatotoxic activities of Dasatinib. The metabolism of Acetaminophen can be decreased when combined with Rabeprazole. The metabolism of Acetaminophen can be increased when combined with Hexobarbital. The metabolism of Acetaminophen can be decreased when combined with Metoprolol. The serum concentration of Acetaminophen can be increased when it is combined with Ivacaftor. The metabolism of Acetaminophen can be increased when combined with Rifampicin. The metabolism of Acetaminophen can be decreased when combined with Delavirdine. The metabolism of Acetaminophen can be decreased when combined with Felodipine. The risk or severity of adverse effects can be increased when Lisuride is combined with Acetaminophen. The serum concentration of Acetaminophen can be increased when it is combined with Lumacaftor. The serum concentration of Acetaminophen can be decreased when it is combined with Enzalutamide. The metabolism of Acetaminophen can be decreased when combined with Sulfadiazine. The serum concentration of Brentuximab vedotin can be increased when it is combined with Acetaminophen. The serum concentration of Acetaminophen can be increased when it is combined with Netupitant. The metabolism of Acetaminophen can be decreased when combined with Cyclosporine. The serum concentration of Pazopanib can be increased when it is combined with Acetaminophen. The serum concentration of Acetaminophen can be increased when it is combined with Darunavir. The metabolism of Acetaminophen can be decreased when combined with Sulfisoxazole. The risk or severity of adverse effects can be increased when Dapsone is combined with Acetaminophen. The metabolism of Acetaminophen can be increased when combined with Barbital. The risk or severity of adverse effects can be increased when Nicergoline is combined with Acetaminophen. The serum concentration of Acetaminophen can be decreased when it is combined with Bosentan. The metabolism of Acetaminophen can be decreased when combined with Posaconazole. The metabolism of Acetaminophen can be decreased when combined with Dosulepin. The metabolism of Acetaminophen can be decreased when combined with Lobeglitazone. The metabolism of Acetaminophen can be decreased when combined with Doxycycline. The metabolism of Acetaminophen can be decreased when combined with Methotrimeprazine. The serum concentration of Acetaminophen can be increased when it is combined with Stiripentol. The metabolism of Acetaminophen can be increased when combined with Rifabutin. The serum concentration of Acetaminophen can be decreased when it is combined with Dabrafenib. The serum concentration of Acetaminophen can be increased when it is combined with Fusidic Acid. The metabolism of Acetaminophen can be decreased when combined with Mexiletine. The metabolism of Acetaminophen can be decreased when combined with Tenofovir disoproxil. The metabolism of Acetaminophen can be decreased when combined with Theophylline.