The metabolism of Terbinafine can be decreased when combined with Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Leuprolide. Rosoxacin may increase the hypoglycemic activities of Pioglitazone. The serum concentration of Pioglitazone can be increased when it is combined with Lumacaftor. The metabolism of Pioglitazone can be decreased when combined with Cobicistat. The metabolism of Mirtazapine can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Omeprazole. The metabolism of Domperidone can be decreased when combined with Pioglitazone. Iproniazid may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Itraconazole. Gatifloxacin may increase the hypoglycemic activities of Pioglitazone. Aminosalicylic Acid may increase the hypoglycemic activities of Pioglitazone. The metabolism of Apixaban can be decreased when combined with Pioglitazone. Toloxatone may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Quinine. The metabolism of Pioglitazone can be decreased when combined with Crizotinib. The metabolism of Erlotinib can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Telaprevir. The serum concentration of Pioglitazone can be increased when it is combined with Simeprevir. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Methyclothiazide. The metabolism of Pioglitazone can be decreased when combined with Fluconazole. Fluoxymesterone may increase the hypoglycemic activities of Pioglitazone. The metabolism of Ixazomib can be decreased when combined with Pioglitazone. Cinoxacin may increase the hypoglycemic activities of Pioglitazone. Phenelzine may increase the hypoglycemic activities of Pioglitazone. The serum concentration of Pioglitazone can be increased when it is combined with Osimertinib. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Tacrolimus. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Niacin. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Medroxyprogesterone acetate. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Prednisone. The metabolism of Temazepam can be decreased when combined with Pioglitazone. Dihydrotestosterone may increase the hypoglycemic activities of Pioglitazone. Rasagiline may increase the hypoglycemic activities of Pioglitazone. Salicylic acid may increase the hypoglycemic activities of Pioglitazone. The serum concentration of Metoprolol can be increased when it is combined with Pioglitazone. Testosterone Propionate may increase the hypoglycemic activities of Pioglitazone. Furazolidone may increase the hypoglycemic activities of Pioglitazone. Hydracarbazine may increase the hypoglycemic activities of Pioglitazone. Indalpine may increase the hypoglycemic activities of Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Olanzapine. Pegvisomant may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Topiroxostat. Balsalazide may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Ticagrelor. The metabolism of Mefenamic acid can be decreased when combined with Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Drospirenone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Desogestrel. The serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Pioglitazone. Pioglitazone may increase the hypoglycemic activities of Disopyramide. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Epinephrine. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Bendroflumethiazide. Gemifloxacin may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Fosamprenavir. The metabolism of Vortioxetine can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Verapamil. The metabolism of Simvastatin can be decreased when combined with Pioglitazone. The metabolism of Riociguat can be decreased when combined with Pioglitazone. Pioglitazone may increase the hypoglycemic activities of Mecasermin. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Pasireotide. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Dienogest. Procarbazine may increase the hypoglycemic activities of Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Buserelin. The metabolism of Eszopiclone can be decreased when combined with Pioglitazone. The metabolism of Methadone can be decreased when combined with Pioglitazone. The metabolism of Repaglinide can be decreased when combined with Pioglitazone. Trans-2-Phenylcyclopropylamine may increase the hypoglycemic activities of Pioglitazone. The serum concentration of Thioridazine can be increased when it is combined with Pioglitazone. The metabolism of Ketamine can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Venlafaxine. The metabolism of Pioglitazone can be decreased when combined with Tamoxifen. The metabolism of Nicotine can be decreased when combined with Pioglitazone. The metabolism of Rofecoxib can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Rucaparib. The metabolism of Chloroquine can be decreased when combined with Pioglitazone. The metabolism of Benzyl alcohol can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Ticlopidine. The metabolism of Pioglitazone can be decreased when combined with Etravirine. The metabolism of Warfarin can be decreased when combined with Pioglitazone. Escitalopram may increase the hypoglycemic activities of Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Cyclopenthiazide. Pioglitazone may increase the hypoglycemic activities of Insulin Detemir. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Lanreotide. Methylene blue may increase the hypoglycemic activities of Pioglitazone. The metabolism of Odanacatib can be decreased when combined with Pioglitazone. Pioglitazone may increase the hypoglycemic activities of Nateglinide. Aloxiprin may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Leflunomide. The metabolism of Voxilaprevir can be decreased when combined with Pioglitazone. The risk or severity of adverse effects can be increased when Pioglitazone is combined with Insulin Human. Duloxetine may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Capecitabine. The metabolism of Zopiclone can be decreased when combined with Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Sirolimus. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Hydroflumethiazide. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Articaine. The metabolism of Lapatinib can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Floxuridine. The metabolism of Pioglitazone can be decreased when combined with Telithromycin. The metabolism of Pioglitazone can be decreased when combined with Nelfinavir. Tranylcypromine may increase the hypoglycemic activities of Pioglitazone. Pioglitazone may increase the hypoglycemic activities of Chlorpropamide. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Dexamethasone. The metabolism of Pioglitazone can be increased when combined with Rifabutin. The metabolism of Pioglitazone can be increased when combined with Phenytoin. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Clozapine. The metabolism of Pioglitazone can be decreased when combined with Fluorouracil. The metabolism of Theophylline can be decreased when combined with Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Sulfamethoxazole. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Corticotropin. The metabolism of Almotriptan can be decreased when combined with Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Estradiol. The serum concentration of Rilpivirine can be decreased when it is combined with Pioglitazone. The metabolism of Pazopanib can be decreased when combined with Pioglitazone. Fluoxetine may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Dosulepin. Norfloxacin may increase the hypoglycemic activities of Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Cortisone acetate. Minaprine may increase the hypoglycemic activities of Pioglitazone. The metabolism of Pioglitazone can be decreased when combined with Celecoxib. The metabolism of Atorvastatin can be decreased when combined with Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Temsirolimus. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Methylprednisolone. The metabolism of Dasabuvir can be decreased when combined with Pioglitazone. Dapoxetine may increase the hypoglycemic activities of Pioglitazone. Stanozolol may increase the hypoglycemic activities of Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Vorinostat. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Etonogestrel. The metabolism of Pioglitazone can be decreased when combined with Valproic Acid. Pivhydrazine may increase the hypoglycemic activities of Pioglitazone. The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Tipranavir.