The risk or severity of adverse effects can be increased when Alprazolam is combined with Quetiapine. The serum concentration of Alprazolam can be increased when it is combined with Telaprevir. The metabolism of Alprazolam can be increased when combined with Primidone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Midazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Lidocaine. The serum concentration of Alprazolam can be increased when it is combined with Fosamprenavir. The risk or severity of adverse effects can be increased when Alprazolam is combined with Indiplon. The risk or severity of adverse effects can be increased when Alprazolam is combined with Prilocaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Perphenazine. The therapeutic efficacy of Alprazolam can be decreased when used in combination with Aminophylline. The risk or severity of adverse effects can be increased when Alprazolam is combined with Isoflurane. The risk or severity of adverse effects can be increased when Alprazolam is combined with Clorazepate. The risk or severity of adverse effects can be increased when Alprazolam is combined with Indalpine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ropivacaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Cetirizine. The metabolism of Alprazolam can be increased when combined with Secobarbital. The risk or severity of adverse effects can be increased when Alprazolam is combined with Agomelatine. The metabolism of Alprazolam can be decreased when combined with Isradipine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Pipotiazine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Protriptyline. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Methadone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Hexobarbital. The risk or severity of adverse effects can be increased when Alprazolam is combined with Methylphenobarbital. The risk or severity of adverse effects can be increased when Alprazolam is combined with Gamma Hydroxybutyric Acid. The risk or severity of adverse effects can be increased when Alprazolam is combined with Etomidate. The risk or severity of adverse effects can be increased when Alprazolam is combined with Dyclonine. The serum concentration of Alprazolam can be increased when it is combined with Dabigatran etexilate. The risk or severity of adverse effects can be increased when Alprazolam is combined with Gabapentin. The metabolism of Alprazolam can be decreased when combined with Trimethoprim. Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Desloratadine. The serum concentration of Alprazolam can be increased when it is combined with Boceprevir. The risk or severity of adverse effects can be increased when Alprazolam is combined with Fluphenazine. The serum concentration of Alprazolam can be increased when it is combined with Candoxatrilat. The risk or severity of adverse effects can be increased when Alprazolam is combined with Melatonin. Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Thiamylal. The serum concentration of Pitavastatin can be increased when it is combined with Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Nalbuphine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Trimipramine. The risk or severity of adverse effects can be increased when Cabergoline is combined with Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Levocabastine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Phenoxyethanol. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. The risk or severity of adverse effects can be increased when Alprazolam is combined with Dexbrompheniramine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Dapiprazole. The risk or severity of adverse effects can be increased when Alprazolam is combined with Fencamfamine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Gepirone. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. The metabolism of Alprazolam can be decreased when combined with Dosulepin. The metabolism of Alprazolam can be decreased when combined with Zafirlukast. The risk or severity of adverse effects can be increased when Alprazolam is combined with Flurazepam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Tiagabine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Triprolidine. The serum concentration of Alprazolam can be increased when it is combined with Racecadotril. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ethyl carbamate. The risk or severity of adverse effects can be increased when Ergotamine is combined with Alprazolam. The serum concentration of Rosuvastatin can be increased when it is combined with Alprazolam. The serum concentration of Alprazolam can be increased when it is combined with Clarithromycin. Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Alprazolam. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. The serum concentration of Alprazolam can be increased when it is combined with Ombitasvir. The risk or severity of adverse effects can be increased when Alprazolam is combined with Bromazepam. The therapeutic efficacy of Alprazolam can be decreased when used in combination with Ambroxol acefyllinate. The serum concentration of Alprazolam can be increased when it is combined with Cilastatin. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ketazolam. The metabolism of Alprazolam can be decreased when combined with Ticlopidine. The metabolism of Alprazolam can be decreased when combined with Cholecalciferol. The metabolism of Alprazolam can be decreased when combined with Ranolazine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Perazine. The metabolism of Alprazolam can be decreased when combined with Atomoxetine. The metabolism of Alprazolam can be decreased when combined with Posaconazole. The risk or severity of adverse effects can be increased when Alprazolam is combined with Clonazepam. The metabolism of Alprazolam can be decreased when combined with Manidipine. The risk or severity of adverse effects can be increased when Alprazolam is combined with DPDPE. The risk or severity of adverse effects can be increased when Alprazolam is combined with Cocaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Levodopa. The risk or severity of adverse effects can be increased when Alprazolam is combined with Tizanidine. The serum concentration of Alprazolam can be increased when it is combined with Trandolapril. The risk or severity of adverse effects can be increased when Alprazolam is combined with Proparacaine. The serum concentration of Bosutinib can be increased when it is combined with Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Levocetirizine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Methaqualone. The metabolism of Alprazolam can be decreased when combined with Gemfibrozil. The risk or severity of adverse effects can be increased when Alprazolam is combined with Cyproheptadine. The serum concentration of Alprazolam can be increased when it is combined with Asunaprevir. The risk or severity of adverse effects can be increased when Alprazolam is combined with Lurasidone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Zimelidine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Oxycodone. The metabolism of Alprazolam can be decreased when combined with Crizotinib. The serum concentration of Alprazolam can be increased when it is combined with Enalapril. The risk or severity of adverse effects can be increased when Alprazolam is combined with Mepivacaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Etidocaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Aripiprazole. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. The risk or severity of adverse effects can be increased when Alprazolam is combined with Ramelteon. The risk or severity of adverse effects can be increased when Alprazolam is combined with Triflupromazine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Flibanserin. The risk or severity of adverse effects can be increased when Alprazolam is combined with Cinchocaine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Tetrahydropalmatine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Etizolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Diazepam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Fluticasone propionate. The metabolism of Alprazolam can be decreased when combined with Venlafaxine. Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Alphacetylmethadol. The risk or severity of adverse effects can be increased when Alprazolam is combined with Amisulpride. The risk or severity of adverse effects can be increased when Alprazolam is combined with Brotizolam. The serum concentration of Phenytoin can be increased when it is combined with Alprazolam. The risk or severity of adverse effects can be increased when Alprazolam is combined with Escitalopram. The risk or severity of adverse effects can be increased when Alprazolam is combined with Thiopental. The metabolism of Alprazolam can be decreased when combined with Fluconazole. The metabolism of Alprazolam can be decreased when combined with Voriconazole. The risk or severity of adverse effects can be increased when Alprazolam is combined with Pramocaine. The metabolism of Alprazolam can be decreased when combined with Floxuridine. The serum concentration of Alprazolam can be increased when it is combined with Fusidic Acid. The serum concentration of Alprazolam can be increased when it is combined with Ximelagatran. The risk or severity of adverse effects can be increased when Alprazolam is combined with Levetiracetam. The serum concentration of Alprazolam can be increased when it is combined with Cilazapril. The serum concentration of Alprazolam can be decreased when it is combined with Brigatinib. The serum concentration of Mevastatin can be increased when it is combined with Alprazolam. Alprazolam may increase the sedative activities of Metyrosine. The risk or severity of adverse effects can be increased when Alprazolam is combined with Drotebanol. The serum concentration of Alprazolam can be increased when it is combined with Ixazomib. The risk or severity of adverse effects can be increased when Alprazolam is combined with Iloperidone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Metaxalone. The risk or severity of adverse effects can be increased when Alprazolam is combined with Benperidol. The risk or severity of adverse effects can be increased when Alprazolam is combined with Amperozide. The risk or severity of adverse effects can be increased when Alprazolam is combined with Flunarizine. The serum concentration of Alprazolam can be increased when it is combined with Tipranavir.