Drug combination: Betaloc sr & Prestance & Letrox & Stacyl & Olwexya

Compared drugs
Betaloc sr (metoprolol)
Prestance (perindopril and amlodipine)
Letrox (levothyroxine sodium)
Stacyl (acetylsalicylic acid)
Olwexya (venlafaxine)
Drug Interaction
Betaloc sr & Prestance
The serum concentration of Metoprolol can be increased when it is combined with Amlodipine.

Betaloc sr & Stacyl
Acetylsalicylic acid may decrease the antihypertensive activities of Metoprolol.

Betaloc sr & Olwexya
The serum concentration of Metoprolol can be increased when it is combined with Venlafaxine.

Prestance & Olwexya
The metabolism of Amlodipine can be decreased when combined with Venlafaxine.

Letrox & Olwexya
The metabolism of Levothyroxine can be decreased when combined with Venlafaxine.

Stacyl & Olwexya
Venlafaxine may increase the antiplatelet activities of Acetylsalicylic acid.

Food interactions and other recommendations

Betaloc sr: Avoid alcohol. Avoid natural licorice. Take with food.
Prestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Letrox: Absorption increased in fasting state and decreased in malabsorption states. Consistent administration in relation to meals is recommended. No iron or calium carbonate within 4 hours of taking this medication. Oral administration with infant soybean formula, soybean flour, cotton seed meal, walnuts, foods containing large amounts of fiber, ferrous sulfate, and antacids may decrease drug absorption. Take 30-60 minutes before breakfast.
Stacyl: Avoid alcohol, alcohol appears to cause a 50 to 100% increases in ASA serum levels. Take with a full glass of water. Take with food to reduce gastric irritation.
Olwexya: Avoid alcohol. Avoid St.John's Wort. Take with food.
 
 
Combination of side effects
Combination of common side effects of all medicines
For some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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