Drug combination: Prestance & Aspirin & Lokren

Compared drugs
Prestance (perindopril and amlodipine)
Aspirin (acetylsalicylic acid)
Lokren (betaxolol)
Drug Interaction
Prestance & Lokren
The risk or severity of adverse effects can be increased when Betaxolol is combined with Amlodipine.

Aspirin & Lokren
Acetylsalicylic acid may decrease the antihypertensive activities of Betaxolol.

Food interactions and other recommendations

Prestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Aspirin: Avoid alcohol, alcohol appears to cause a 50 to 100% increases in ASA serum levels. Take with a full glass of water. Take with food to reduce gastric irritation.
 
 
Combination of side effects
Combination of common side effects of all medicines
For some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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