Drug combination: Triplixam & Milurit 100 & Betamed & Eliquis & Metfogamma 850 & Sortis
Drug InteractionTriplixam & Betamed
The risk or severity of adverse effects can be increased when Betaxolol is combined with Amlodipine.
Triplixam & Sortis
The risk or severity of adverse effects can be increased when Amlodipine is combined with Atorvastatin.
Eliquis & Sortis
The serum concentration of Atorvastatin can be increased when it is combined with Apixaban.
Food interactions and other recommendationsTriplixam: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Milurit 100: Avoid alcohol. Take with a full glass of water. Take with food.
Eliquis: Alfalfa, Anise, Bilberry may increase the adverse effects of apixaban. Grapefruit juice may increase apixaban serum concentration. St. John's wort will likely decrease apixaban serum concentration. Avoid combination if possible.
Metfogamma 850: Avoid alcohol. Take with food to reduce gastric irritation.
Sortis: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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