Drug combination: Betaloc sr & Helicid 10 zentiva & Ibalgin 200 & Asentra 100 & Propafenon al 150

Compared drugs
Betaloc sr (metoprolol)
Helicid 10 zentiva (omeprazole)
Ibalgin 200 (ibuprofen)
Asentra 100 (sertraline)
Propafenon al 150 (propafenone)
Drug Interaction
Betaloc sr & Helicid 10 zentiva
The serum concentration of Metoprolol can be increased when it is combined with Omeprazole.

Betaloc sr & Ibalgin 200
Ibuprofen may decrease the antihypertensive activities of Metoprolol.

Betaloc sr & Asentra 100
The serum concentration of Metoprolol can be increased when it is combined with Sertraline.

Betaloc sr & Propafenon al 150
The serum concentration of Metoprolol can be increased when it is combined with Propafenone.

Helicid 10 zentiva & Ibalgin 200
The metabolism of Ibuprofen can be decreased when combined with Omeprazole.

Helicid 10 zentiva & Asentra 100
The metabolism of Sertraline can be decreased when combined with Omeprazole.

Ibalgin 200 & Asentra 100
The metabolism of Ibuprofen can be decreased when combined with Sertraline.

Asentra 100 & Propafenon al 150
Sertraline may increase the QTc-prolonging activities of Propafenone.

Food interactions and other recommendations

Betaloc sr: Avoid alcohol. Avoid natural licorice. Take with food.
Helicid 10 zentiva: Avoid alcohol. Take 30-60 minutes before meals.
Ibalgin 200: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
Asentra 100: Avoid alcohol. Avoid St.John's Wort. Avoid taking with grapefruit juice. Take with food.
Propafenon al 150: Always take at the same time in regard to meals. Grapefruit and grapefruit juice should be avoided throughout treatment. Grapefruit can increase serum levels of this product.
 
Combination of side effects
Combination of common side effects of all medicines
Constipation
Betaloc sr (common)
Helicid 10 zentiva (common)
Ibalgin 200 (very common)
Asentra 100 (uncommon)
Propafenon al 150 (uncommon)

Diarrhea
Betaloc sr (common)
Helicid 10 zentiva (very common)
Ibalgin 200 (common)
Asentra 100 (uncommon)
Propafenon al 150 (uncommon)

Dizziness
Betaloc sr (common)
Helicid 10 zentiva (common)
Ibalgin 200 (very common)
Asentra 100 (uncommon)
Propafenon al 150 (common)

Flatulence
Betaloc sr (common)
Helicid 10 zentiva (common)
Ibalgin 200 (very common)
Asentra 100 (common)
Propafenon al 150 (uncommon)

Headache
Betaloc sr (common)
Helicid 10 zentiva (common)
Ibalgin 200 (very common)
Asentra 100 (uncommon)
Propafenon al 150 (uncommon)

Nausea
Betaloc sr (common)
Helicid 10 zentiva (common)
Ibalgin 200 (very common)
Asentra 100 (uncommon)
Propafenon al 150 (very common)

Vomiting
Betaloc sr (common)
Helicid 10 zentiva (common)
Ibalgin 200 (very common)
Asentra 100 (common)
Propafenon al 150 (uncommon)

Somnolence
Betaloc sr (uncommon)
Helicid 10 zentiva (common)
Ibalgin 200 (very common)
Asentra 100 (uncommon)
Propafenon al 150 (uncommon)


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