Drug combination: Klacid 500 & Lipfix

Compared drugs
Klacid 500 (clarithromycin)
Lipfix (atorvastatin)

Drug Interaction

Klacid 500 & Lipfix
The serum concentration of Atorvastatin can be increased when it is combined with Clarithromycin.

Food interactions and other recommendations

Klacid 500: Biaxin - take without regard to meals (however absorption appears to be improved when drug is taken with food). Biaxin XL - take with a meal, taking it on an empty stomach is associated with total product exposure 30% inferior to that observed when administered with food.
Lipfix: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.

Combination of side effects

Combination of common side effects of all medicines

Abdominal Pain
Klacid 500 (common)
Lipfix (common)

Asthenia
Klacid 500 (common)
Lipfix (common)

Back pain
Klacid 500 (uncommon)
Lipfix (common)

Constipation
Klacid 500 (common)
Lipfix (common)

Diarrhea
Klacid 500 (common)
Lipfix (uncommon)

Dyspepsia
Klacid 500 (common)
Lipfix (common)

rash
Klacid 500 (common)
Lipfix (common)

Flatulence
Klacid 500 (uncommon)
Lipfix (common)

Headache
Klacid 500 (common)
Lipfix (very common)

flu
Klacid 500 (uncommon)
Lipfix (common)

Nausea
Klacid 500 (uncommon)
Lipfix (uncommon)

Pharyngitis
Klacid 500 (common)
Lipfix (common)

ALT increased
Klacid 500 (common)
Lipfix (uncommon)

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