Drug combination: Lorista 12,5 & Ibalgin 400 & Agen 5 &
Drug InteractionLorista 12,5 & Ibalgin 400
The metabolism of Ibuprofen can be decreased when combined with Losartan.
Lorista 12,5 & Agen 5
The risk or severity of adverse effects can be increased when Amlodipine is combined with Losartan.
Lorista 12,5 &
The risk or severity of adverse effects can be increased when Lisuride is combined with Losartan.
Ibalgin 400 &
The risk or severity of adverse effects can be increased when Ketorolac is combined with Ibuprofen.
Agen 5 &
The serum concentration of Rosuvastatin can be increased when it is combined with Amlodipine.
Food interactions and other recommendationsLorista 12,5: Take without regard to meals. Take at same time each day. Food delays absorption, but does not affect the extent of absorption.
Ibalgin 400: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
Agen 5: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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