Drug combination: Bisoprolol mylan & Emanera & Kreon 25 000 & Lusopress & Pragiola & Zaldiar & Brufen 400

Compared drugs
Bisoprolol mylan (bisoprolol)
Emanera (esomeprazole)
Kreon 25 000 (multienzymes (lipase, protease etc.))
Lusopress (nitrendipine)
Pragiola (pregabalin)
Zaldiar (tramadol and paracetamol)
Brufen 400 (ibuprofen)
Drug Interaction
Bisoprolol mylan & Lusopress
Bisoprolol may increase the hypotensive activities of Nitrendipine.

Bisoprolol mylan & Zaldiar - drug name Zaldiar - we do not have enough data to compare, please contact us by email and we will send you a comparison additionally
Bisoprolol mylan & Brufen 400
Ibuprofen may decrease the antihypertensive activities of Bisoprolol.

Emanera & Zaldiar - drug name Zaldiar - we do not have enough data to compare, please contact us by email and we will send you a comparison additionally
Emanera & Brufen 400
The metabolism of Ibuprofen can be decreased when combined with Esomeprazole.

Kreon 25 000 & Zaldiar - drug name Zaldiar - we do not have enough data to compare, please contact us by email and we will send you a comparison additionally
Lusopress & Zaldiar - drug name Zaldiar - we do not have enough data to compare, please contact us by email and we will send you a comparison additionally
Pragiola & Zaldiar - drug name Zaldiar - we do not have enough data to compare, please contact us by email and we will send you a comparison additionally
Zaldiar & Brufen 400 - drug name Zaldiar - we do not have enough data to compare, please contact us by email and we will send you a comparison additionally
Food interactions and other recommendations

Bisoprolol mylan: Take without regard to meals.
Emanera: Take without regard to meals.
Kreon 25 000: Delayed release capsules should not be broken or crushed, but for those patients who cannot swallow the capsules, sprinkle the contents of the capsule onto soft acidic foods (pH of ≤4.5). Alkaline foods with a higher pH will promote early release of pancrelipase followed by enzyme inactivation in the stomach. Multivitamins/minerals which have vitamins ADEK, folate, or iron: If pancrelipase is used in combination with multivitamins/minerals that have vitamins ADEK, folate, or iron then monitor therapy because pancrelipase may decrease absorption of iron in these multivitamin/mineral products. Take pancrelipase with meals and a sufficient amount of water.
Pragiola: Avoid alcohol (may increase CNS effects). When taken with food, Cmax decreases, while Tmax is prolonged. Despite these observations, the total absorption of pregabalin is not effected to a clinically relevant degree. Pregabalin can be taken with or without food.
Brufen 400: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
 
 
Combination of side effects
Combination of common side effects of all medicines
For some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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