The metabolism of Ibuprofen can be decreased when combined with Sulfisoxazole. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Parecoxib. The therapeutic efficacy of Chlorothiazide can be decreased when used in combination with Ibuprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Benoxaprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Fluorometholone. The risk or severity of adverse effects can be increased when Lisinopril is combined with Ibuprofen. Ibuprofen may increase the neuroexcitatory activities of Pefloxacin. The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ibuprofen. The metabolism of Ibuprofen can be decreased when combined with Tranylcypromine. Ibuprofen may decrease the antihypertensive activities of Nebivolol. Ibuprofen may decrease the excretion rate of Aclarubicin which could result in a higher serum level. The metabolism of Ibuprofen can be decreased when combined with Tamoxifen. The metabolism of Ibuprofen can be decreased when combined with Tolbutamide. The risk or severity of adverse effects can be increased when Eprosartan is combined with Ibuprofen. The therapeutic efficacy of Trichlormethiazide can be decreased when used in combination with Ibuprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Fluprednidene. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Estrone sulfate. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Tiaprofenic acid. Ibuprofen may increase the anticoagulant activities of Phenindione. The risk or severity of adverse effects can be increased when Trandolapril is combined with Ibuprofen. The therapeutic efficacy of Bimatoprost can be decreased when used in combination with Ibuprofen. Ibuprofen may decrease the antihypertensive activities of Acebutolol. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Metamizole. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Indoprofen. Ibuprofen may increase the anticoagulant activities of Dextran 40. Ibuprofen may decrease the antihypertensive activities of Bucindolol. Ibuprofen may increase the anticoagulant activities of Gabexate. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Paramethasone. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Triamcinolone. Ibuprofen may increase the anticoagulant activities of Sulodexide. The risk or severity of adverse effects can be increased when Candesartan is combined with Ibuprofen. The metabolism of Ibuprofen can be decreased when combined with Floxuridine. The therapeutic efficacy of Dinoprost Tromethamine can be decreased when used in combination with Ibuprofen. The risk or severity of adverse effects can be increased when Etodolac is combined with Ibuprofen. The therapeutic efficacy of Dinoprostone can be decreased when used in combination with Ibuprofen. Ibuprofen may increase the anticoagulant activities of Dabigatran etexilate. The risk or severity of adverse effects can be increased when Ibuprofen is combined with PTC299. The risk or severity of adverse effects can be increased when Naftifine is combined with Ibuprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Atamestane. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Difluprednate. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Ibuproxam. The metabolism of Ibuprofen can be decreased when combined with Pyrimethamine. The serum concentration of Ibuprofen can be increased when it is combined with Abiraterone. Sarilumab may increase the immunosuppressive activities of Ibuprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Benzydamine. The risk or severity of adverse effects can be increased when Rescinnamine is combined with Ibuprofen. Ibuprofen may decrease the antihypertensive activities of Metoprolol. The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Ibuprofen. Ibuprofen may increase the anticoagulant activities of Becaplermin. Ibuprofen may decrease the excretion rate of Valrubicin which could result in a higher serum level. The risk or severity of adverse effects can be increased when Enalaprilat is combined with Ibuprofen. The therapeutic efficacy of Prostaglandin B2 can be decreased when used in combination with Ibuprofen. The metabolism of Ibuprofen can be decreased when combined with Valproic Acid. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Tarenflurbil. The risk or severity of adverse effects can be increased when Enalapril is combined with Ibuprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Formestane. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Aldosterone. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Serrapeptase. The risk or severity of adverse effects can be increased when Imidapril is combined with Ibuprofen. The metabolism of Ibuprofen can be decreased when combined with Delavirdine. The metabolism of Ibuprofen can be decreased when combined with Topiramate. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Equilin. The metabolism of Ibuprofen can be decreased when combined with Fluorouracil. Ibuprofen may decrease the excretion rate of Epirubicin which could result in a higher serum level. Ibuprofen may decrease the excretion rate of Sisomicin which could result in a higher serum level. Ibuprofen may increase the anticoagulant activities of Ancrod. Ibuprofen may increase the anticoagulant activities of Pentaerythritol Tetranitrate. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Loxoprofen. Ibuprofen may increase the neuroexcitatory activities of Cinoxacin. The risk or severity of adverse effects can be increased when Ibuprofen is combined with ME-609. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Apocynin. Ibuprofen may increase the anticoagulant activities of Letaxaban. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Niflumic Acid. The metabolism of Ibuprofen can be decreased when combined with Chloramphenicol. Ibuprofen may decrease the antihypertensive activities of Amiloride. Ibuprofen may decrease the excretion rate of Idarubicin which could result in a higher serum level. The risk or severity of adverse effects can be increased when Olmesartan is combined with Ibuprofen. The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ibuprofen. Ibuprofen may increase the neuroexcitatory activities of Norfloxacin. The risk or severity of adverse effects can be increased when Ramipril is combined with Ibuprofen. The risk or severity of adverse effects can be increased when Mefenamic acid is combined with Ibuprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Alclometasone. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Ibandronate. The metabolism of Ibuprofen can be decreased when combined with Fluvastatin. The metabolism of Ibuprofen can be decreased when combined with Valsartan. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Clobetasol propionate. The risk or severity of adverse effects can be increased when Diflunisal is combined with Ibuprofen. The metabolism of Ibuprofen can be decreased when combined with Felodipine. The serum concentration of Ibuprofen can be increased when it is combined with Mifepristone. The metabolism of Ibuprofen can be increased when combined with Aprepitant. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Fludrocortisone. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Medrysone. Ibuprofen may increase the neuroexcitatory activities of Trovafloxacin. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Rimexolone. The metabolism of Ibuprofen can be decreased when combined with Zafirlukast. The serum concentration of Pralatrexate can be increased when it is combined with Ibuprofen. The risk or severity of adverse effects can be increased when Zofenopril is combined with Ibuprofen. The metabolism of Ibuprofen can be decreased when combined with Dosulepin. The metabolism of Ibuprofen can be increased when combined with Phenytoin. Ibuprofen may increase the anticoagulant activities of Certoparin. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Salicylamide. Ibuprofen may decrease the antihypertensive activities of Atenolol. Ibuprofen may decrease the excretion rate of Kanamycin which could result in a higher serum level. Ibuprofen may decrease the excretion rate of Neomycin which could result in a higher serum level. Ibuprofen may increase the anticoagulant activities of Apixaban. The metabolism of Ibuprofen can be decreased when combined with Rucaparib. The serum concentration of Ibuprofen can be increased when it is combined with Vemurafenib. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Kebuzone. Ibuprofen may increase the anticoagulant activities of Ferulic acid. The risk or severity of adverse effects can be increased when Bromfenac is combined with Ibuprofen. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Zomepirac. Ibuprofen may decrease the excretion rate of Spectinomycin which could result in a higher serum level. Ibuprofen may increase the anticoagulant activities of Reviparin. Ibuprofen may increase the anticoagulant activities of Nadroparin. Ibuprofen may increase the anticoagulant activities of Citric Acid. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Zaltoprofen. The metabolism of Ibuprofen can be decreased when combined with Crisaborole. Ibuprofen may increase the anticoagulant activities of Desirudin. The metabolism of Ibuprofen can be decreased when combined with Ticagrelor. The risk or severity of adverse effects can be increased when Mycophenolate mofetil is combined with Ibuprofen. Ibuprofen may decrease the antihypertensive activities of Hydralazine. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Seratrodast. Ibuprofen may decrease the antihypertensive activities of Talinolol. The serum concentration of Imatinib can be decreased when it is combined with Ibuprofen. Ibuprofen may increase the anticoagulant activities of Darexaban. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Magnesium salicylate. The risk or severity of adverse effects can be increased when Ibuprofen is combined with Mizoribine. The risk or severity of bleeding can be increased when Betrixaban is combined with Ibuprofen. The metabolism of Ibuprofen can be decreased when combined with Isoniazid. The metabolism of Ibuprofen can be increased when combined with Primidone.