Drug combination: Prestance & Duodart
Compared drugsPrestance (perindopril and amlodipine)
Duodart (tamsulosin and dutasteride)
Drug InteractionPrestance & Duodart
Tamsulosin may increase the hypotensive activities of Amlodipine.
Food interactions and other recommendationsPrestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Duodart: Take 30 minutes after a meal (always after the same meal). Taking the drug with food minimizes plasma levels variations.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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