Drug combination: Eliquis & Paralen 100 & Brufen &
Drug InteractionEliquis & Brufen
Ibuprofen may increase the anticoagulant activities of Apixaban.
Eliquis &
The serum concentration of Apixaban can be decreased when it is combined with Pentobarbital.
Paralen 100 &
The serum concentration of Simvastatin can be increased when it is combined with Acetaminophen.
Brufen &
The risk or severity of adverse effects can be increased when Ketorolac is combined with Ibuprofen.
Food interactions and other recommendationsEliquis: Alfalfa, Anise, Bilberry may increase the adverse effects of apixaban. Grapefruit juice may increase apixaban serum concentration. St. John's wort will likely decrease apixaban serum concentration. Avoid combination if possible.
Paralen 100: Avoid alcohol (may increase risk of hepatotoxicity). Take without regard to meals.
Brufen: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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