Drug combination: Tonarssa & Prenessa
Drug InteractionTonarssa & Prenessa
The risk or severity of adverse effects can be increased when Amlodipine is combined with Perindopril.
Food interactions and other recommendationsTonarssa: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Prenessa: Herbs that may attenuate the antihypertensive effect of perindopril include: bayberry, blue cohash, cayenne, ephedra, ginger, ginseng (American), kola and licorice. High salt intake may attenuate the antihypertensive effect of perindopril. Perindopril may decrease the excretion of potassium. Salt substitutes containing potassium may increase the risk of hyperkalemia. Take without regard to meals.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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