Drug combination: Anafranil 25 & Cipralex & Lyrica

Compared drugs
Anafranil 25 (clomipramine)
Cipralex (escitalopram)
Lyrica (pregabalin)

Drug Interaction

Anafranil 25 & Cipralex
The risk or severity of adverse effects can be increased when Clomipramine is combined with Escitalopram.

Anafranil 25 & Lyrica
The therapeutic efficacy of Clomipramine can be increased when used in combination with Pregabalin.

Cipralex & Lyrica
The risk or severity of adverse effects can be increased when Pregabalin is combined with Escitalopram.

Food interactions and other recommendations

Anafranil 25: Avoid alcohol. Grapefruit and grapefruit juice should be avoided throughout treatment, grapefruit can modify serum levels of clomipramine and its metabolite desmethyl-clomipramine. Take with food to reduce irritation.
Cipralex: Take without regard to meals.
Lyrica: Avoid alcohol (may increase CNS effects). When taken with food, Cmax decreases, while Tmax is prolonged. Despite these observations, the total absorption of pregabalin is not effected to a clinically relevant degree. Pregabalin can be taken with or without food.

Combination of side effects

Combination of common side effects of all medicines

Abdominal Pain
Anafranil 25 (very common)
Cipralex (common)
Lyrica (common)

Alopecia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

amenorrhoea
Anafranil 25 (uncommon)
Cipralex (common)
Lyrica (uncommon)

Anemia
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Anorexia
Anafranil 25 (very common)
Cipralex (common)
Lyrica (common)

Anxiety
Anafranil 25 (common)
Cipralex (common)
Lyrica (common)

Arrhythmia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Arthralgia
Anafranil 25 (common)
Cipralex (common)
Lyrica (common)

Asthenia
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (very common)

ataxia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Back pain
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

Bronchitis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

cellulitis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Chest pain
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

colitis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Confusion
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

conjunctivitis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (common)

Constipation
Anafranil 25 (very common)
Cipralex (common)
Lyrica (very common)

cystitis
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

deafness
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Dysphagia
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

depersonalization
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

diabetes
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Diarrhea
Anafranil 25 (very common)
Cipralex (common)
Lyrica (common)

Dizziness
Anafranil 25 (very common)
Cipralex (very common)
Lyrica (very common)

Taste perversion
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

Dysmenorrhea
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

dyspnea
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

dysuria
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Ear pain
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Eczema
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Edema
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (common)

Epistaxis
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

esophagitis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Fatigue
Anafranil 25 (very common)
Cipralex (common)
Lyrica (very common)

fever
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

Flatulence
Anafranil 25 (common)
Cipralex (common)
Lyrica (common)

gastritis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Gastrointestinal Disorders
Anafranil 25 (common)
Cipralex (very common)
Lyrica (common)

gingivitis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

gout
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

hallucinations
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Headache
Anafranil 25 (very common)
Cipralex (very common)
Lyrica (very common)

Hematuria
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

hypercholesterolaemia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

hyperglycemia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

allergic reactions
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

postural hypotension
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

arthropathy
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Renal Calculus
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

laryngitis
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Cramps leg
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (common)

Breast pain
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

menstrual disorder
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

hypertonia
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

Nausea
Anafranil 25 (very common)
Cipralex (very common)
Lyrica (very common)

nervousness
Anafranil 25 (very common)
Cipralex (common)
Lyrica (uncommon)

neuralgia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

otitis media
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

Pain
Anafranil 25 (common)
Cipralex (common)
Lyrica (common)

Palpitation
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

paresthesia
Anafranil 25 (common)
Cipralex (common)
Lyrica (common)

Pneumonia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (common)

polyuria
Anafranil 25 (uncommon)
Cipralex (common)
Lyrica (uncommon)

prostate
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Itching
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

psoriasis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

psychosis
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

rhinitis
Anafranil 25 (very common)
Cipralex (common)
Lyrica (common)

Seizure
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

increased salivation
Anafranil 25 (uncommon)
Cipralex (common)
Lyrica (uncommon)

Sinusitis
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

speech disorder
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

suicide attempt
Anafranil 25 (uncommon)
Cipralex (common)
Lyrica (uncommon)

Syncope
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Tachycardia
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

Thirst
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Tinnitus
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

TOOTH DISORDER
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

tremor
Anafranil 25 (very common)
Cipralex (common)
Lyrica (uncommon)

Urinary frequency
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

urinary incontinence
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

urticaria
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

vaginitis
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

vertigo
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Vomiting
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

Weight gain
Anafranil 25 (very common)
Cipralex (common)
Lyrica (very common)

Weight decrease
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

Dry mouth
Anafranil 25 (very common)
Cipralex (uncommon)
Lyrica (very common)

urinary retention
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Chills
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

agitation
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

apathy
Anafranil 25 (uncommon)
Cipralex (common)
Lyrica (uncommon)

hypokinesia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Migraine
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

muscle weakness
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (common)

eye pain
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

increased alkaline phosphatase
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

skin discoloration
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Dry skin
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

accommodation abnormal
Anafranil 25 (uncommon)
Cipralex (common)
Lyrica (uncommon)

photosensitivity reaction
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Malaise
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Myalgia
Anafranil 25 (very common)
Cipralex (common)
Lyrica (common)

Twitch
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

Increased appetite
Anafranil 25 (very common)
Cipralex (common)
Lyrica (common)

disorientation
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

thinking abnormal
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (uncommon)

Memory impairment
Anafranil 25 (common)
Cipralex (uncommon)
Lyrica (common)

euphoria
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (common)

impotence
Anafranil 25 (very common)
Cipralex (common)
Lyrica (common)

hemorrhage rectal
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Blurred vision
Anafranil 25 (very common)
Cipralex (common)
Lyrica (uncommon)

maculopapular rash
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

hyper
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Bradycardia
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

lymphadenopathy
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

abnormal coordination
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

abnormal electrocardiogram
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

Gait Abnormal
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

sleep disorder
Anafranil 25 (common)
Cipralex (common)
Lyrica (uncommon)

Insomnia
Anafranil 25 (very common)
Cipralex (very common)
Lyrica (very common)

Somnolence
Anafranil 25 (very common)
Cipralex (very common)
Lyrica (very common)

Vaginal hemorrhage
Anafranil 25 (uncommon)
Cipralex (uncommon)
Lyrica (uncommon)

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