Drug combination: Anafranil 25 & Cipralex & Lyrica & Presid & Nolpaza
Drug InteractionAnafranil 25 & Cipralex
The risk or severity of adverse effects can be increased when Clomipramine is combined with Escitalopram.
Anafranil 25 & Lyrica
The therapeutic efficacy of Clomipramine can be increased when used in combination with Pregabalin.
Anafranil 25 & Presid
The risk or severity of adverse effects can be increased when Clomipramine is combined with Felodipine.
Anafranil 25 & Nolpaza
The metabolism of Clomipramine can be decreased when combined with Pantoprazole.
Cipralex & Lyrica
The risk or severity of adverse effects can be increased when Pregabalin is combined with Escitalopram.
Cipralex & Nolpaza
The metabolism of Escitalopram can be decreased when combined with Pantoprazole.
Food interactions and other recommendationsAnafranil 25: Avoid alcohol. Grapefruit and grapefruit juice should be avoided throughout treatment, grapefruit can modify serum levels of clomipramine and its metabolite desmethyl-clomipramine. Take with food to reduce irritation.
Cipralex: Take without regard to meals.
Lyrica: Avoid alcohol (may increase CNS effects). When taken with food, Cmax decreases, while Tmax is prolonged. Despite these observations, the total absorption of pregabalin is not effected to a clinically relevant degree. Pregabalin can be taken with or without food.
Presid: Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of nifedipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of nifedipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Nolpaza: Take without regard to meals.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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