Drug combination: Helicid 20 zentiva & Pragiola & Trittico ac 150

Compared drugs
Helicid 20 zentiva (omeprazole)
Pragiola (pregabalin)
Trittico ac 150 (trazodone)

Drug Interaction

Pragiola & Trittico ac 150
The therapeutic efficacy of Trazodone can be increased when used in combination with Pregabalin.

Food interactions and other recommendations

Helicid 20 zentiva: Avoid alcohol. Take 30-60 minutes before meals.
Pragiola: Avoid alcohol (may increase CNS effects). When taken with food, Cmax decreases, while Tmax is prolonged. Despite these observations, the total absorption of pregabalin is not effected to a clinically relevant degree. Pregabalin can be taken with or without food.
Trittico ac 150: Avoid alcohol. Food decreases the rate and extent of absorption.

Combination of side effects

Combination of common side effects of all medicines

Back pain
Helicid 20 zentiva (uncommon)
Pragiola (uncommon)
Trittico ac 150 (common)

Constipation
Helicid 20 zentiva (common)
Pragiola (very common)
Trittico ac 150 (common)

Diarrhea
Helicid 20 zentiva (very common)
Pragiola (common)
Trittico ac 150 (common)

Dizziness
Helicid 20 zentiva (common)
Pragiola (very common)
Trittico ac 150 (very common)

Fatigue
Helicid 20 zentiva (uncommon)
Pragiola (very common)
Trittico ac 150 (very common)

Headache
Helicid 20 zentiva (common)
Pragiola (very common)
Trittico ac 150 (uncommon)

Nausea
Helicid 20 zentiva (common)
Pragiola (very common)
Trittico ac 150 (uncommon)

paresthesia
Helicid 20 zentiva (uncommon)
Pragiola (common)
Trittico ac 150 (common)

Itching
Helicid 20 zentiva (uncommon)
Pragiola (common)
Trittico ac 150 (common)

vertigo
Helicid 20 zentiva (common)
Pragiola (uncommon)
Trittico ac 150 (uncommon)

Vomiting
Helicid 20 zentiva (common)
Pragiola (common)
Trittico ac 150 (very common)

Dry mouth
Helicid 20 zentiva (common)
Pragiola (very common)
Trittico ac 150 (very common)

Malaise
Helicid 20 zentiva (uncommon)
Pragiola (uncommon)
Trittico ac 150 (common)

Blurred vision
Helicid 20 zentiva (uncommon)
Pragiola (uncommon)
Trittico ac 150 (very common)

Insomnia
Helicid 20 zentiva (common)
Pragiola (very common)
Trittico ac 150 (common)

Somnolence
Helicid 20 zentiva (common)
Pragiola (very common)
Trittico ac 150 (common)

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