Methotrexat accord & Ibalgin 400 The serum concentration of Methotrexate can be increased when it is combined with Ibuprofen.
Food interactions and other recommendations
Methotrexat accord: Milk appears to reduce its absorption. Take without regard to meals. Limit caffeine intake. Paracetamol apotex: Avoid alcohol (may increase risk of hepatotoxicity). Take without regard to meals. Ibalgin 400: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
Combination of side effects
Combination of common side effects of all medicines