Drug combination: Timonil 600 retard & Ibalgin 400 & Baclofen-polpharma & Rivotril

Compared drugs
Timonil 600 retard (carbamazepine)
Ibalgin 400 (ibuprofen)
Baclofen-polpharma (baclofen)
Rivotril (clonazepam)
Drug Interaction
Timonil 600 retard & Ibalgin 400
The metabolism of Ibuprofen can be increased when combined with Carbamazepine.

Timonil 600 retard & Baclofen-polpharma
The risk or severity of adverse effects can be increased when Carbamazepine is combined with Baclofen.

Timonil 600 retard & Rivotril
The metabolism of Clonazepam can be increased when combined with Carbamazepine.

Baclofen-polpharma & Rivotril
The risk or severity of adverse effects can be increased when Baclofen is combined with Clonazepam.

Food interactions and other recommendations

Timonil 600 retard: Avoid alcohol. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Take with food, increases availability and reduces irritation.
Ibalgin 400: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
Baclofen-polpharma: Avoid alcohol. Take without regard to meals.
Rivotril: Avoid alcohol. Avoid excessive quantities of coffee or tea (Caffeine). Take without regard to meals.
 
Combination of side effects
Combination of common side effects of all medicines
Constipation
Timonil 600 retard (common)
Ibalgin 400 (very common)
Baclofen-polpharma (uncommon)
Rivotril (common)

Dizziness
Timonil 600 retard (very common)
Ibalgin 400 (very common)
Baclofen-polpharma (common)
Rivotril (uncommon)

Somnolence
Timonil 600 retard (very common)
Ibalgin 400 (very common)
Baclofen-polpharma (very common)
Rivotril (very common)


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