Drug combination: Prestance & Brufen 400 &
Drug InteractionPrestance &
The serum concentration of Rosuvastatin can be increased when it is combined with Amlodipine.
Brufen 400 &
The risk or severity of adverse effects can be increased when Ketorolac is combined with Ibuprofen.
Food interactions and other recommendationsPrestance: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Brufen 400: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
Combination of side effects Combination of common side effects of all medicinesFor some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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