Drug combination: Dormicum & Zyprexa & Betaloc zok & Ibalgin rapid

Compared drugs
Dormicum (midazolam)
Zyprexa (olanzapine)
Betaloc zok (metoprolol)
Ibalgin rapid (ibuprofen)
Drug Interaction
Dormicum & Zyprexa
The risk or severity of adverse effects can be increased when Midazolam is combined with Olanzapine.

Zyprexa & Betaloc zok
The serum concentration of Metoprolol can be increased when it is combined with Olanzapine.

Betaloc zok & Ibalgin rapid
Ibuprofen may decrease the antihypertensive activities of Metoprolol.

Food interactions and other recommendations

Dormicum: Grapefruit juice slows the product's absorption and significantly increases its bioavailability.
Zyprexa: Avoid alcohol. Take without regard to meals.
Betaloc zok: Avoid alcohol. Avoid natural licorice. Take with food.
Ibalgin rapid: Avoid alcohol Food delays the time to reach peak plasma concentrations by 30-60 minutes and reduces peak plasma concentrations by 30-50%. Extent of absorption is unaffected. Take with food to reduce gastric irritation.
 
Combination of side effects
Combination of common side effects of all medicines
Headache
Dormicum (common)
Zyprexa (very common)
Betaloc zok (common)
Ibalgin rapid (very common)

Nausea
Dormicum (uncommon)
Zyprexa (common)
Betaloc zok (common)
Ibalgin rapid (very common)

Itching
Dormicum (uncommon)
Zyprexa (uncommon)
Betaloc zok (common)
Ibalgin rapid (uncommon)

Vomiting
Dormicum (uncommon)
Zyprexa (uncommon)
Betaloc zok (common)
Ibalgin rapid (very common)

Somnolence
Dormicum (common)
Zyprexa (very common)
Betaloc zok (uncommon)
Ibalgin rapid (very common)


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