Drug combination: Concor combi & Tezefort & Metformin mylan & Oltar & Atoris 20 & Itoprid pmcs

Compared drugs
Concor combi (bisoprolol and amlodipine)
Tezefort (telmisartan and amlodipine)
Metformin mylan (metformin)
Oltar (glimepiride)
Atoris 20 (atorvastatin)
Itoprid pmcs (itopride)
Drug Interaction
Concor combi & Tezefort
The risk or severity of adverse effects can be increased when Amlodipine is combined with Bisoprolol.

Concor combi & Oltar
Bisoprolol may increase the hypoglycemic activities of Glimepiride.

Tezefort & Atoris 20
The risk or severity of adverse effects can be increased when Amlodipine is combined with Atorvastatin.

Metformin mylan & Oltar
Metformin may increase the hypoglycemic activities of Glimepiride.

Oltar & Atoris 20
Atorvastatin may increase the hypoglycemic activities of Glimepiride.

Food interactions and other recommendations

Concor combi: Take without regard to meals.
Tezefort: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Metformin mylan: Avoid alcohol. Take with food to reduce gastric irritation.
Oltar: Avoid alcohol. Even though food reduces product absorption, the manufacturer recommends taking the product with the first meal of the day.
Atoris 20: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.
 
Combination of side effects
Combination of common side effects of all medicines
For some of the comparators, there is not enough information available, contact us by email and we will list the side effects additionally
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About project

A freely available non-commercial project for the purpose of laic drug comparisons at the level of interactions, side effects as well as drug prices and their alternatives

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